O-Glycoprotease (IMPa) is a broad specificity protease that cleaves the peptide bonds of a glycoprotein or glycopeptide immediately N-terminal to a serine or threonine residue containing a mucin-type O-linked glycan with or without sialylation.

• Enables O-glycosylation site mapping and O-glycan structural profiling
• Efficiently cleaves adjacent to O-glycans with or without sialic acid, no neuraminidase treatment necessary
• Recombinant enzyme with no detectable non-specific protease contaminating activities
• Can be used under native or denaturing conditions
• Glycerol-free for optimal performance in HPLC and mass spectrometry analysis
• Supplied in solution; optimal activity and stability for up to 24 months