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APE 1
- Apurinic/apyrimidinic Endonuclease 1
- DNA AP endonuclease that catalyzes the cleavage of DNA phosphodiester backbone at AP sites via hydrolysis leaving a 1 nucleotide gap with 3′-hydroxyl and 5′ deoxyribose phosphate (dRP) termini
- APE 1 has also been reported to have DNA 3′-diesterase, 3′ to 5′ exonuclease, and RNase H activities
- Also known as HAP1 or Ref-1
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What are endonucleases and their applications?
Endonuclease IV |NEB酶试剂 New England Biolabs
上海金畔生物科技有限公司代理New England Biolabs(NEB)酶试剂全线产品,欢迎访问官网了解更多产品信息和订购。
Endonuclease IV
- DNA AP endonuclease
- Catalyzes the cleavage of DNA phosphodiester backbone at AP sites via hydrolysis leaving a 1 nucleotide gap with 3′-hydroxyl and 5′ deoxyribose phosphate (dRP) termini
- Also has 3′-diesterase activity which can remove 3′ phosphate, 3′-α, β-unsaturated aldehyde, phosphoglycoaldehyde, and other 3′ blocking groups
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What are endonucleases and their applications?
Endonuclease V |NEB酶试剂 New England Biolabs
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Endonuclease V
The large size of this product has been discontinued.
- DNA endonuclease
- Catalyzes the cleavage of the second DNA phosphodiester backbone 3′ to deoxyinosine, leaving a 3′-OH and 5′ – phosphate
- Endonuclease V activity, to a lesser extent, is also reported on AP site, urea, mismatches, hairpins, loops, and pseudo-Y structures
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What are endonucleases and their applications?
hAAG |NEB酶试剂 New England Biolabs
上海金畔生物科技有限公司代理New England Biolabs(NEB)酶试剂全线产品,欢迎访问官网了解更多产品信息和订购。
hAAG
The large size of this product has been discontinued.
- Human Alkyl Adenine DNA Glycosylase
- Monofunctional DNA glycosylase that catalyzes the hydrolysis of the N-glycosidic bond to release damaged base
- Recognizes a wide variety of alkylated and oxidized purines
- Major substrates include 3-methyladenine, 7-methylguanine, 1,N6-ethenoadenine, and hypoxanthine
- Minor substrates include deoxyinosine and deoxyxanthosine
- Also known as methylpurine DNA glycosylase (MPG) and alkyl-N-purine DNA glycosylase (ANPG)
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What are endonucleases and their applications?
RecA |NEB酶试剂 New England Biolabs
上海金畔生物科技有限公司代理New England Biolabs(NEB)酶试剂全线产品,欢迎访问官网了解更多产品信息和订购。
RecA
RecA is necessary for genetic recombination reactions involving DNA repair and UV-induced mutagenesis
- Visualization of DNA structures with electron microscopy
- D-loop mutagenesis
- Screening libraries using RecA-coated probes
- Cleavage of DNA at a single predetermined site
- RecA mediated affinity capture for full length cDNA cloning
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What are endonucleases and their applications?
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