MG132溶液 (10mM/L)

上海金畔生物科技有限公司提供MG132溶液 (10mM/L) ,欢迎访问官网了解更多产品信息。

产品编号 D50396s
英文名称 MG-132 solution (10mM/L)
中文名称 MG132溶液 (10mM/L)
别    名 MG132; Z-LLL-CHO; Z-Leu-Leu-Leu-CHO; Z-Leu-Leu-Leu-al; Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal; proteasome inhibitor;   Proteasome抑制剂; 蛋白酶体抑制剂;
保存条件 Store at -80°C for 6 month.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 MG-132 is a peptide aldehyde and a potent, reversible, and cell-permeable proteasome inhibitor with an IC50 of 100 nM, and effectively blocks the proteolytic activity of the 26S proteasome complex.

* 本产品为:MG-132 solution (10mM/L) in DMSO。

MG-132 产品信息:
CAS:133407-82-6
分子式:C26H41N3O5
分子量:475.62
MDL:MFCD00674886
纯度:≥98%
外观/性状:白色粉末
熔点:250-253℃
沸点:682℃ at 760 mmHg
闪点:366.3℃
溶解性:溶于DMSO。
敏感性:易吸潮
作用靶点:Proteasome; Autophagy; Apoptosis;
作用通路:Metabolic Enzyme/Protease; Autophagy; Apoptosis;
用途及描述:MG-132 是一种多肽醛,也是有效的,可逆的,可透过细胞的蛋白酶体抑制剂,IC50 值为 100 nM,有效地阻断了 26S 蛋白酶体复合物的蛋白水解活性。也被用来测试海胆胚胎中的泛素化和去甲酰化途径。A proteasome and NF-κB inhibitor.