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Sodium Orthovanadate (Vanadate)
Vanadate has been fully activated.
Sodium Orthovanadate (Vanadate) is a general competitive inhibitor for protein phosphotyrosyl phosphatases. The inhibition by Sodium Orthovanadate is reversible upon the addition of EDTA or by dilution.
- Can be used to preserve the protein tyrosyl phosphorylation state in cells, cell lysates, and protein tyrosine kinase assays
- Commonly used in combination with Sodium Fluoride (NEB# P0759) to inhibit Lambda Protein Phosphatase activity (NEB# P0753)