nordicbioscience胶原蛋白形成生物标志物
|
Assay name |
Assay description |
Volume required (uL) |
|
PRO-C1 |
Internal epitope in the N-terminal pro-peptide of type I collagen |
50 |
|
PRO-C2 |
Released N-terminal pro-peptide of type II collagen |
50 |
|
PRO-C3 |
Released N-terminal pro-peptide of type III collagen |
50 |
|
PC3X |
Cross-linked N-terminal pro-peptide of type III collagen |
50 |
|
iP3NP |
Internal epitope in the N-terminal pro-peptide of type III collagen |
50 |
|
PRO-C4 |
Internal epitope in the 7S domain of type IV collagen |
50 |
|
PRO-C5 |
Released C-terminal pro-peptide of type V collagen |
50 |
|
PRO-C6 |
C-terminal of released C5 domain of type VI collagen α3 chain (endotrophin) |
50 |
|
PRO-C8 |
C-terminal of type VIII collagen |
50 |
|
PRO-C10 |
C-terminal of type X |
50 |
|
PRO-C11 |
Released N-terminal pro-peptide of type XI collagen |
50 |
|
PRO-C16 |
C-terminal of Type XVI collagen |
50 |
|
PRO-C18 |
N-terminal type XVIII collagen |
50 |
|
PRO-C18L |
N-terminal of the type XVIII collagen medium and long isoforms |
50 |
|
PRO-C19 |
C-terminal of type XIX collagen |
50 |
|
PRO-C23 |
C-terminal of type XXIII collagen |
50 |
|
PRO-C28 |
C-terminal of type XXVIII collagen |
50 |
Collagen degradation biomarkers
|
Assay name |
Assay description |
Volume required (uL) |
|
C1M |
Neo-epitope of MMP-2,9,13 mediated degradation of type I collagen |
50 |
|
C2M |
Neo-epitope of MMP mediated degradation of type II collagen |
80 |
| T2CM | Neo-epitope of MMP-1 and -13 mediated degradation of type II collagen | 50 |
|
C3M |
Neo-epitope of MMP-9 mediated degradation of type III collagen |
50 |
|
urine C3M |
Neo-epitope of MMP-9 mediated degradation of type III collagen |
50 |
|
C3A |
Neo-epitope of ADAMTS-4,5 mediated degradation of type III collagen |
50 |
|
C3C |
Neo-epitope of cathepsin-B,L,S mediated degradation of type III collagen |
50 |
|
C4M |
Neo-epitope of MMP-2,9,12 mediated degradation of type IV collagen alpha 1 chain |
50 |
|
C4Ma3 |
Neo-epitope of MMP-2,9,12 mediated degradation of type IV collagen alpha 3 chain |
50 |
|
TUM |
MMP-9 mediated release of tumstatin from type IV collagen alpha 3 chain |
50 |
|
urine C4M |
Neo-epitope of MMP-2,9,12 mediated degradation of type IV collagen alpha 1 chain |
50 |
|
C4G |
Neo-epitope of granzyme B mediated degradation of type IV collagen |
50 |
|
C5M |
Neo-epitope of MMP-2,9 mediated degradation of type V collagen |
50 |
|
C6M |
Neo-epitope of MMP-2 mediated degradation of type VI collagen |
50 |
|
C6Ma3 |
Neo-epitope of MMP-9 mediated degradation of type VI collagen |
50 |
|
C7M |
Neo-epitope of type MMP-13 mediated decradation of type VII collagen |
50 |
|
C10C |
Neo-epitope of cathepsin-K mediated decradation of type X collagen |
50 |
| Col10NC | Neo-epitope of the NC domain of type X collagen | 50 |
| CTX-I | Neo-epitope of cathepsin mediated degradation of type I collagen | 50 |
| CTX-II (Urine) |
Neo-epitope of MMP mediated degradation of type II collagen |
100 |
| CTX-III |
Cross-linked type III collagen C-terminal telopeptide |
50 |
Elastin based biomarkers
|
Assay name |
Assay description |
Volume required (uL) |
|
|
EL-CG |
|
50 |
|
|
ELM |
|
80 |
|
|
ELM12 |
|
50 |
|
|
ELM7 |
|
50 |
|
|
EL-NE |
|
50 |
|
|
ELP-3 |
Neo-epitope of proteinase-3 mediated degradation of elastin | 50 |
Wound healing biomarkers
|
Assay name |
Assay description |
Volume required (uL) |
|
PRO-FIB |
Neo-epitope of thrombin mediated degradation of fibrinogen |
50 |
|
X-FIB |
Neo-epitope of plasmin mediated degradation of cross-linked fibrin (sandwich assay) |
80 |
|
FXIIIAP |
Neo-epitope of thrombin mediated degradation of transglutaminase FXIII |
50 |
|
vWF-A |
Neo-epitope of ADAMTS13 mediated degradation of von willebrand factor |
50 |
|
vWF-N |
Released N-terminal pro-peptide of von willebrand factor |
50 |
|
F1.2/F2 |
Neo-epitope of Fxa/Fva mediated degradation of prothrombin |
50 |
|
F1 |
Neo-epitope of thrombin mediated degradation of prothrombin | 50 |
| T-FIB
|
Neo-epitope of plasmin mediated degradation of fibrin |
50 |
Extracellular matrix associated biomarkers
|
Assay name |
Assay description |
Volume required (uL) |
|
a-SMA |
Acetylated N-terminal of alpha-smooth muscle actin |
50 |
|
BGM |
Neo-epitope of MMP-9,12 mediated degradation of biglycan |
50 |
|
DCN-CS |
Cathepsin S mediated decorin degradation |
50 |
|
HSP47-C |
C-terminal of heat shock protein-47 |
50 |
|
LAM |
Neo-epitope of MMP-9 mediated degradation of laminin alpha 5 chain |
50 |
|
LG1M |
Neo-epitope of MMP-9 mediated degradation of laminin gamma 1 chain |
50 |
|
MIM |
Neo-epitope of MMP-9,12 mediated degradation of mimecan |
50 |
|
NIC |
Neo-epitope of cathepsin-S mediated degradation of nidogen |
50 |
|
SPARC-M |
Neo-epitope of MMP mediated degracation of SPARC |
50 |
|
TIM |
Neo-epiotpe of MMP-12 mediated degradation of titin (Cardiac isoform) |
50 |
|
TIM-2 |
Specific fragment of MMP-12-mediated degradation of titin (Muscle isoform) |
50 |
|
VCANM |
Neo-epitope of MMP-8,12 mediated degradation of versican |
50 |
|
VICM |
Neo- epitope of MMP-2, 8 and trypsin mediated degradation of citrullinated vimentin |
50 |
|
ARGS |
N-terminal epitope of Aggrecanase mediated degradation of aggrecan |
50 |
|
FBN-C |
C-terminal of fibronectin
|
50 |
|
CPa9-HNE |
Neo-epitope fo human neutrophil elastase (HNE) mediated degradatib if calprotectin
|
50 |
|
PROM |
Neo-epitope of MMP-1 and -13 mediated degradation of prolargin |
50 |
|
uPerla |
Neo-epiotpe of ADAMTS mediated degradation of perlecan |
50 |
|
exAGNxI |
Neo-epitope of aggrenase mediated aggrecan |
50 |
|
exFFGV |
Neo-epitope of MMP mediated aggrecan |
50 |
|
BREM |
Brevican degraded by MMPs |
50 |
|
BREV-A |
Neo-epitope of ADAMTS-4 mediated degradation of brevican |
50 |
|
n-BREV |
N-terminal of brevican |
50 |
|
TAU-A |
Neo-epitope of ADAM-10 mediated degradation of TAU |
50 |
|
TAU-C |
Neo-epitope of caspase-3 mediated degradation of TAU |
50 |
|
exMMP3 |
Activated MMP-3 |
50 |
|
acCAT-K |
Activated Cathepsin K |
50 |
|
acMMP-9 |
Activated MMP-9 |
50 |
|
acMMP-13 |
N-terminal of active MMP-13 |
50 |
|
acADAMTS4 |
N-terminal of active ADAMTS-4 |
50 |
|
acADAMTS5 |
N-terminal of active ADAMTS-5 |
50 |
|
COMP-N |
N-terminal of COMP |
50 |
|
SPARC-C |
C-terminal of SPARC |
50 |
|
AGR-N |
N-terminal of agrin |
50 |
|
FBN-EDA |
Neo-epitope of MMP-8 mediated degradation of cellular fibronectin (EDA domain) |
50 |
|
FMODM |
Fibromodulin degraded by MMP-12 |
50 |
Other biomarkers
|
Assay name |
Assay description |
Volume required (uL) |
|
GDF-8 |
Myostatin (growth/differentiation factor 8) |
150 |
|
IL-6 |
Interleukin-6 |
250 |
|
FMODM |
Fibromodulin degraded by MMP-12 |
50 |
|
Ostase BAP |
Bone-specific Alkaline Phosphatase ELISA |
100 |
|
PIIANP |
Type IIA Collagen N-Propeptide (PIIANP) ELISA |
10 |
|
C-P-Tau (181P) |
Phosphorylated Tau (P181) |
50 |
|
C-β-Amyloid (1-42) |
Amyloid Beta 1-42 |
50 |
|
HCG |
Chorionic Gonadotropin (pregnancy test) |
10 |
|
PTH, intact |
Parathyroid hormone |
50 |
|
S-Free T4 |
thyroxine |
15 |
|
S-Testosterone |
testosterone |
20 |
|
S-Total T3 |
Total triiodothyronine |
30 |
|
S-TSH |
thyroid stimulating hormone |
50 |
|
Total PINP |
N-terminal pro-peptide of type I collagen |
20 |
|
Anti-CCP |
Anti-citrullinated protein antibodies |
15 |
|
Anti-HCV |
Antibodies to hepatitis C virus |
50 |
|
HBsAg II |
Hepatitis B surface antigen |
50 |
|
HIV combi PT |
HIV-1 P24 antigen, antibodies against HIV-1 and HIV-2 |
40 |
|
HIV-Ag |
HIV-1 P24 antigen group M and O |
50 |
|
Insulin |
Insulin |
20 |
|
S-Albumin |
Albumin |
2 |
|
S-ALAT |
Alanine transaminase |
25 |
|
S-ASAT |
Aspartate transaminase |
25 |
|
S-Bilirubin |
Total billirubin |
14.3 |
|
S-Calcium |
Serum calcium |
16 |
|
S-Cholesterol |
Serum cholesterol |
4 |
|
S-Creatinine |
Serum creatinine |
24 |
|
S-GGT |
Gamma-glutamyltransferase |
10 |
|
S-Glucose |
Glucose |
3.4 |
|
S-protein |
Total serum protein |
17.5 |
|
S-Urea |
Serum urea |
7 |
|
S-HDL Cholesterol |
Serum HDL cholesterol |
5 |
|
S-LDL Cholesterol |
Serum LDL cholesterol |
5 |
|
Urine Calcium |
Urine calcium |
16 |
|
Urine Creatinine |
Urine Creatinine |
24 |
|
Urine Phosphat |
Urine Phosphat |
8 |
|
S-Phosphat |
Serum phosphat |
8 |
|
S-Magnesium |
Serum magnesium |
12 |
|
S-Lipase |
Serum lipase |
3 |
|
S-Amylase |
Serum amylase |
16 |
|
S-LDH |
Serum LDH |
14 |
|
S-CO2 |
Serum CO2 |
6 |
|
ELF |
65 |