BioPorto ABS 033-10B-005 说明书

上海金畔生物专业代理并分销BioPorto糖尿病、肥胖症等代谢疾病相关的单克隆抗体。蛋白质/多肽类激素通常是产生于特定刺激后分泌到循环系统中的激素原,一旦分泌,大多数的肽激素在血液循环自由存在。在穿越血液循环的同时,在靶细胞表面遇到受体,并与特定的内分泌细胞上的细胞表面受体结合。内分泌细胞合成,储存和分泌蛋白质/多肽激素,并再次激活各种信号转导系统,内分泌的紊乱会引起多种代谢疾病。

糖尿病相关

胰高血糖素样肽-1(GLP-1) 存在多种剪切体,包括GLP-1 Extended form、GLP-1 Active form及GLP-1 Metabolite等。BioPorto专业提供针对各种形式GLP-1的单克隆抗体,用于GLP-1糖尿病治疗的研究及检测,为早期研发阶段、临床阶段I和/或在zui终治疗产品的生产和质量控制过程提供可靠依据。

图1 不同形式的GLP-1 (Glucagon-likepeptide1)示意图

提供胰高血糖素样肽-2(GLP-2)、胰多肽(PP)、Exendin-4、胰高血糖素(Glucagon)等糖尿病研究相关单克隆抗体:

货号

产品名称

规格

宿主

应用

ABS 033-04-02

Glucagon-like peptide-1 (GLP-1(7-37) and GLP-1(7-36)amide, N-terminal specific)

200µl

Mouse

ELISA, IHC

ABS 033-04-1

Glucagon-like peptide-1 (GLP-1(7-37) and GLP-1(7-36)amide, N-terminal specific)

1ml

Mouse

ELISA, IHC

ABS 033-10-02

Glucagon-like peptide-1 (GLP-1(7-37) and GLP-1(7-36)amide, N-terminal specific)

200µl

Mouse

ELISA, WB

ABS 033-10-1

Glucagon-like peptide-1 (GLP-1(7-37) and GLP-1(7-36)amide, N-terminal specific)

1ml

Mouse

ELISA, WB

ABS 033-10B-005

Glucagon-like peptide-1 (GLP-1(7-37) and GLP-1(7-36)amide, N-terminal specific)

50µl

Mouse

ELISA

ABS 044-49-02

Glucagon-like peptide-1 (GLP-1(9-37) and GLP-1(9-36)amide, N-terminal specific)

200µl

Mouse

ELISA, WB

ABS 044-49-1

Glucagon-like peptide-1 (GLP-1(9-37) and GLP-1(9-36)amide, N-terminal specific)

1ml

Mouse

ELISA, WB

ABS 044-53-02

Glucagon-like peptide-1 (GLP-1(9-37) and GLP-1(9-36)amide, N-terminal specific)

200µl

Mouse

ELISA, WB

ABS 044-53-1

Glucagon-like peptide-1 (GLP-1(9-37) and GLP-1(9-36)amide, N-terminal specific)

1ml

Mouse

ELISA, WB

ABS 046-03-02

Glucagon-like peptide-1 (GLP-1, Non-amidated (-Arg-Gly), C-terminal specific)

200µl

Mouse

ELISA, WB

ABS 046-03-1

Glucagon-like peptide-1 (GLP-1, Non-amidated (-Arg-Gly), C-terminal specific)

1ml

Mouse

ELISA, WB

ABS 046-03B-005

Glucagon-like peptide-1 (GLP-1, Non-amidated (-Arg-Gly), C-terminal specific)

50µl

Mouse

ELISA

HYB 011-05-02

Glucagon-like peptide-1 (GLP-1(1-36)amide, N-terminal-extension specific)

200µl

Mouse

ELISA, WB

HYB 011-05-1

Glucagon-like peptide-1 (GLP-1(1-36)amide, N-terminal-extension specific)

1ml

Mouse

ELISA, WB

HYB 147-06-02

Glucagon-like peptide-1 (GLP-1 (7-36)amide, C-terminal specific)

200µl

Mouse

ELISA, IHC

HYB 147-06-1

Glucagon-like peptide-1 (GLP-1 (7-36)amide, C-terminal specific)

1ml

Mouse

ELISA, IHC

HYB 147-06B-005

Glucagon-like peptide-1 (GLP-1 (7-36)amide, C-terminal specific)

50µl

Mouse

ELISA

HYB 147-08-02

Glucagon-like peptide-1 (GLP-1, Mid-molecule specific)

200µl

Mouse

ELISA, WB

HYB 147-08-1

Glucagon-like peptide-1 (GLP-1, Mid-molecule specific)

1ml

Mouse

ELISA, WB

HYB 147-08B-005

Glucagon-like peptide-1 (GLP-1, Mid-molecule specific)

50µl

Mouse

ELISA

HYB 147-12-02

Glucagon-like peptide-1 (GLP-1, Mid-molecule specific)

200µl

Mouse

ELISA, WB, IHC

HYB 147-12-1

Glucagon-like peptide-1 (GLP-1, Mid-molecule specific)

1ml

Mouse

ELISA, WB, IHC

HYB 147-12B-005

Glucagon-like peptide-1 (GLP-1, Mid-molecule specific)

50µl

Mouse

ELISA

HYB 147-13-02

Glucagon-like peptide-1 (GLP-1, Mid-molecule specific)

200µl

Mouse

ELISA, WB

HYB 147-13-1

Glucagon-like peptide-1 (GLP-1, Mid-molecule specific)

1ml

Mouse

ELISA, WB

HYB 006-02-02

Glucagon-like peptide-2 (human, GLP-2)

200µl

Mouse

ELISA

HYB 006-02-1

Glucagon-like peptide-2 (human, GLP-2)

1ml

Mouse

ELISA

ABS 030-06-02

Pancreatic Polypeptide (human, PP)

200µl

Mouse

ELISA, WB

ABS 030-06-1

Pancreatic Polypeptide (human, PP)

1ml

Mouse

ELISA, WB

HYB 347-06-02

Pancreatic PolyPeptide (PP)

200µL

Mouse

ELISA

HYB 347-06-1

Pancreatic PolyPeptide (PP)

1ml

Mouse

ELISA

ABS 012-20-02

Exendin-4

200µl

Mouse

ELISA

ABS 012-20-1

Exendin-4

1ml

Mouse

ELISA

ABS 012-24-02

Exendin-4

200µl

Mouse

ELISA

ABS 012-24-1

Exendin-4

1ml

Mouse

ELISA

ABS 012-35-02

Exendin-4

200µl

Mouse

ELISA

ABS 012-35-1

Exendin-4

1ml

Mouse

ELISA

ABS 012-35B-005

Exendin-4

50µl

Mouse

ELISA

ABS 058-08-02

Glucagon (human, pig, rat)

200µl

Mouse

ELISA

ABS 058-08-1

Glucagon (human, pig, rat)

1ml

Mouse

ELISA

ABS 058-08B-005

Glucagon (human, pig, rat)

50µl

Mouse

ELISA

ABS 061-09-02

Glucagon (human, pig, rat)

200µl

Mouse

ELISA

ABS 061-09-1

Glucagon (human, pig, rat)

1ml

Mouse

ELISA

 

Anti-GLP-1(7-37) and GLP-1(7-36)amide (N-terminal specific)

CAT.NO. ABS 033-10B

DELIVERY: 1-5 DAYS

 

Cat. No.

ABS 033-10B

Product name

Anti-GLP-1(7-37) and GLP-1(7-36)amide (N-terminal specific)

Description

Mouse monoclonal antibody, biotinylated

Specificity

ABS 033-10 binds the free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide and shows <0.2% cross-reactivity with GLP-1(9-36)amide, glucagon and human GIP. Cross-reacts 0.25% with GLP-1(1-37), approximay 6% with human GLP-2 and approximay 50% with exendin-4. ABS 033-10 cross-reacts with Liraglutide.聽

Immunogen

Synthetic GLP-1(7-17)聽

Application

ELISA

Species reactivity (positive)

Human

Species reactivity (negative)

Not determined

Subclass

IgG2a/k

Gene ID

2641

Clone number

10

Epitope

Free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide.

Content

50 碌L, 1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification

Biotinylated

Form

Liquid

Solvent

0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15 mM sodium azide

Storage

4-8ºC without exposure to light. No precautions necessary during handling.

Target

Glucagon-like peptide 1(7-36)amide (GLP-1(7-36)amide) is the principal active form of GLP-1, the other being GLP-1(7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.

 

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