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T4 PDG (T4 Endonuclease V)
The large size of this product has been discontinued.
- T4 pyrimidine DNA glycosylase
- Bifunctional DNA glycosylase with DNA N-glycosylase and AP lyase activities
- The N-glycosylase activity releases cis-syn cyclobutane pyrimidine dimers, including T^T, T^C and C^C, generating an AP site. The AP lyase activity cleaves an AP site via β-elimination, creating a 1 nucleotide DNA gap with 3′-α, β-unsaturated aldehyde and 5′-phosphate termini.
- Also known as T4 Endonuclease V
