标签归档：ready

加拿大Silicycle硅胶填料Get ready for the new ICH-Q3D Heavy Metal Regulation

发表于由

上海金畔生物科技有限公司代理加拿大Silicycle硅胶填料色谱柱层析板金属离子清除剂全线产品，欢迎访问官网了解更多产品信息和订购。
Get ready for the new ICH-Q3D Heavy Metal Regulation

Get ready for the new ICH-Q3D Heavy Metal Regulation

Details

White Paper (3 pages)

In recent years, the presence of metal impurities has become a major issue in the drug-making industry, and thus, the need for its effective removal.
For almost two years now, the International Conference on Harmonisation (ICH) has been working on its Q3D guidelines for metal elemental impurities in new drugs and new formulations containing known ingredients. After many revisions and improvements, the final version or the Q3D guidelines was finally accepted and signed off by the ICH Steering Committee in December 2014, hence requiring that the entire manufacturing industry and supply chain follow these regulations.

> Get the PDF version (requires to be logged in)

progen ready-to-use formats停产通知

发表于由

progen ready-to-use formats停产通知

 

接progen厂家通知， ready-to-use formats将于12月底停产，部分有代替产品。

详情如下：

 

货号 停产产品名称 替代品

替代产品货号
70010 anti-Perilipin 1-5 complete sample set no
70011 anti-Perilipin 2,3,5 sample set no
70012 anti-Perilipin 1,2,5 sample set no
70020 anti-Keratin sample set no
70021 anti-skin layer Keratin sample set no
70022 anti-hair Keratin sample set no
70023 anti-Keratin K8/K18 sample set no
70030 anti-Desmosome sample set 1 no
70031 anti-Desmosome sample set 2 no
70032 anti-Desmosome sample set 3 no
70033 anti-Desmoglein 1-4 sample set no
70034 anti-Desmocollin 1 & 3 sample set no
70035 anti-Plakophilin 1-3 sample set no
61036S anti-Keratin K17 mouse monoclonal, Ks17.E3, purified, sample (ready-to-use) 200 µl liquid 690036S
61028S anti-Keratin K18 mouse monoclonal, Ks18.04, purified, sample (ready-to-use) 200 µl liquid 690028S
61029S anti-Keratin K19 mouse monoclonal, Ks19.2 (Z105.6), purified, sample (ready-to-use) 200 µl liquid 690029S
61038S anti-Keratin K8 mouse monoclonal, Ks8.7, purified, sample (ready-to-use) 200 µl liquid 690038S
GP-HHB2S anti-basic Hair Keratin K82 guinea pig polyclonal, serum, sample (ready-to-use) no
GP-HHB5S anti-basic Hair Keratin K85 guinea pig polyclonal, serum, sample (ready-to-use) no
GP-HHB6S anti-basic Hair Keratin K86 guinea pig polyclonal, serum, sample (ready-to-use) no
61092S anti-Desmocollin 1 mouse monoclonal, Dsc1-U100, purified, sample (ready-to-use) 200 µl liquid 690029S
61093S anti-Desmocollin 3 mouse monoclonal, Dsc3-U114, purified, sample (ready-to-use) 200 µl liquid 690093S
651111S anti-Desmoglein 1 mouse monoclonal, Dsg1-P124, supernatant, sample (ready-to-use) no
61002S anti-Desmoglein 1/2 mouse monoclonal, DG 3.10, purified, sample (ready-to-use) 200 µl liquid 690002S
651119S anti-Desmoglein 2 mouse monoclonal, G129, supernatant, sample (ready-to-use) no
651112S anti-Desmoglein 3 mouse monoclonal, Dsg-G194, supernatant, sample (ready-to-use) no
GP4S anti-Desmoglein 4 guinea pig polyclonal, serum, sample (ready-to-use) no
61003S anti-Desmoplakin 1/2 mouse monoclonal, DP1 + 2-2.15, purified, sample (ready-to-use) 200 µl liquid 690003S
11414S anti-Keratin K10 mouse monoclonal, DE-K10, supernatant, sample (ready-to-use) no
GP-CK14S anti-Keratin K14 guinea pig polyclonal, serum, sample (ready-to-use) no
65177S anti-Keratin K2 mouse monoclonal, Ks2.398.3.1, supernatant, sample (ready-to-use) no
GP-K6IRS1S anti-Keratin K71 guinea pig polyclonal, serum, sample (ready-to-use) no
GP-K6IRS2S anti-Keratin K72 guinea pig polyclonal, serum, sample (ready-to-use) no
GP11S anti-Keratin K8/K18 guinea pig polyclonal, serum, sample (ready-to-use) no
GP14S anti-Keratin Pan guinea pig polyclonal, serum, sample (ready-to-use) no
GP29S anti-Perilipin 1 (N-terminus) guinea pig polyclonal, serum, sample (ready-to-use) no
GP40S anti-Perilipin 2 (N-terminus aa 1-29) guinea pig polyclonal, serum, sample (ready-to-use) no
610102S anti-Perilipin 2 (N-terminus) mouse monoclonal, AP125, purified, sample (ready-to-use) 200 µl liquid 6900102S
GP30S anti-Perilipin 3 (N-terminus) guinea pig polyclonal, serum, sample (ready-to-use) no
GP34S anti-Perilipin 4 (C-terminus) guinea pig polyclonal, serum, sample (ready-to-use) no
GP31S anti-Perilipin 5 (C-terminus) guinea pig polyclonal, serum, sample (ready-to-use) no
61005S anti-Plakoglobin mouse monoclonal, PG 5.1, purified, sample (ready-to-use) 200 µl liquid 690005S
65160S anti-Plakophilin 1 mouse monoclonal, PP1-5C2, supernatant, sample (ready-to-use) no
651101S anti-Plakophilin 2 mouse monoclonal, PP2/62 + PP2/86 + PP2/150, supernatant, sample (ready-to-use) no
651113S anti-Plakophilin 3 mouse monoclonal, PKP3-270.6.2, sample (ready-to-use) no

 

inno-train HLA-Ready Plate产品

发表于由

 

inno-train是一家专业从事输血医学和免疫学领域的运营公司。自1998年以来，我们为血型分类生产和分销分子IVD测试系统的家商业供应商。

此外，我们在HLA-typings领域提供完整的产品系列。这包括血清学测试系统，PCR-SSP方法，以及达到高分辨率的测序。为了便于评估我们的测序测试系统，我们提供了一个复杂的软件解决方案

我们内部研发部门的宝贵专业知识使创新诊所能够开发创新诊断，将其作为IVD生产并通过合作伙伴在范围内进行分销。

凭借我们新的FluoGene产品线，我们再次成为家提供基于荧光终点检测的分子血型和HLA型自动化CE标志的公司。

HLA准备板-微淋巴细胞毒性试验

inno-train HLA-Ready Plate产品

 

HLA-Ready Plate

HLA-Ready Plate – Microlymphocytotoxicitytest

  • 解冻准备板10 – 15分钟。使用前
  • 将1μl（2000-3000）淋巴细胞分配到托盘中的每个孔中
  • 在室温下孵育30分钟（DR / DQ：60分钟）
  • 解冻冷冻兔补体重组冻干补体
  • 向每个孔中加入5-6μl兔补体，并在室温下孵育60分钟。
    （DR / DQ：120分钟）
  • 加入3 – 4μleasin（5％），等待5分钟，加入5-6μl甲醛（37％）进行固定
  • 用玻璃载玻片盖住并用倒置相位显微镜读取Ready Plates

阳性细胞的百分比可以以分数报告

  分数1 0 – 10％ 消极反应  
  分数2 11 – 20％ 临界负面反应  
  得分4 21 – 50％ 临界阳性反应  
  得分6 51 – 80％ 积极的反应  
  得分8 81 – 100％ 强烈的积极反应  
  得分0   没有细胞

 

 

Art. No. Name Test / Plate
RUO Not for use in diagnostic procedures – USA and Canada  
002 011 144 HLA-Ready Plate ABC 144 5
002 010 144 HLA-Ready Plate AB 144 5
002 011 120 HLA-Ready Plate ABC 120 5
002 010 120 HLA-Ready Plate AB 120 5
002 012 072 HLA-Ready Plate ABC 72 10
002 014 072 HLA-Ready Plate AB 72 10
002 013 072 HLA-Ready Plate DR 72 10
002 021 001 HLA-Ready Plate B27 1 10
002 022 002 HLA-Ready Plate B27 2 20
002 023 005 HLA-Ready Plate B27 5 50
002 025 005 HLA-Ready Plate ABC Complement 5

 

 

Art. No. Name Test / Plate
RUO Not for use in diagnostic procedures – USA and Canada  
002 041 600 Lymphodex 6 x 100 ml
002 041 500 Lymphodex 500 ml
002 042 600 Hanks Solution 6 x 100 ml
002 042 500 Hanks Solution 500 ml
002 043 500 RPMI-1640 500 ml
002 044 005 Rabbit Complement 5 x 1 ml
002 044 005L Lyophilized Rabbit Complement 5 x 1 ml
002 045 001 HLA Control positive 0.5 ml
002 045 002 HLA Control negative 0.5 ml
002 047 500 Lymphofix 500 ml

FinaBio Ready-to-Conjugate 蛋白

发表于由

Andrew Lees博士于2006年创建了Fina Bio公司，以帮助新兴市场疫苗制造商学会为疫苗生产价格合理的蛋白质多糖偶联物。Fina Bio公司现在是生物技术和疫苗行业联合疫苗实验室和咨询服务的主要供应商。Fina Bio公司位于马里兰州生物技术走廊的中心，毗邻美国国立卫生研究院(NIH)、美国食品和药物管理局(FDA)以及许多生物制药公司。Fina Bio公司有一个设备齐全的实验室，用于分子生物学和蛋白质表达、偶联和偶联疫苗的鉴定。Fina Bio公司的科学家与约翰霍普金斯大学和马里兰大。

FinaBio Ready-to-Conjugate 蛋白

Ready-to-Conjugate Proteins

即型共轭蛋白质类促进结合的新产品

Fina Biosolutions Ready-to-Conjugatecarrier 蛋白通过提供预活化的载体蛋白促进免疫结合物的合成。我们的 Ready-to-Conjugatecarrier 蛋白包括 EcoCRM（FinaBio 的 CRM），以及破伤风毒素重链片段 C (TTHc) 和牛血清白蛋白 (BSA)。这些蛋白用马来酰亚胺或溴乙酸预先标记，并准备与巯基抗原偶联，如半胱氨酸肽和巯基标记的寡糖和多糖。免疫结合物可以很容易地通过 Ready-to-ConjugateCRM-马来酰亚胺和 CRM-溴乙酸盐进行制备和表征。马来酰亚胺-crm 和溴乙酰基-crm 与巯基抗原的反应方案如图 1 所示。将 N-末端半胱氨酸肽 (MW~1.5 kDa) 分别偶联，并通过 SDS PAGE 进行分析。发现各结合物的肽上样水平相似

图 1. 巯基抗原与即配 EcoCRM 的偶联

EcoCRM 是 FinaBio 的 CRM197

 

FinaBio 提供 Ready-to-Conjugate 蛋白，包括 EcoCRM (CRM)、破伤风毒素重链片段 C (TTHc) 和牛血清白蛋白。这些蛋白用马来酰亚胺或溴乙酸预先标记。相关产物包括未标记的 crm 和 TTHc，以及这些蛋白的抗体。Fina Biosolutions 还提供多肽、蛋白质、寡糖和多糖的偶联服务

RNAi-Ready pSIREN-Retro Q-ZsGreen

发表于由

 RNAi载体,RNAi-Ready pSIREN-Retro Q-ZsGreen载体

RNAi-Ready pSIREN-Retro Q-ZsGreen

型号 载体名称 出品公司 载体用途
VRC0347 RNAi-Ready pSIREN-Retro Q-ZsGreen Clontech RNAi载体
产品参数: 

Promoter: Human U6
Reporter: ZsGreen
Selection: prokaryotic—ampicillin
Replication: prokaryotic—Col E1 ori （low copy）, viral—SV40 ori

载体抗性: 
氨苄青霉素（Ampicillin）
载体描述: 

RNAi-Ready pSIREN-RetroQ-ZsGreen derives from our original gene silencing retroviral vector RNAi-Ready pSIREN-RetroQ. pSIREN-RetroQ-ZsGreen is a self-inactivating retroviral expression vector designed to express a small hairpin RNA （shRNA） using the human U6 promoter. This vector is provided as a linearized vector digested with BamH I and EcoR I. It is used for targeted gene silencing when an annealed DNA oligonucleotide encoding an appropriate shRNA is ligated into the vector. The pSIREN-RetroQ-ZsGreen construct can be transfected as a plasmid expression vector. For generation of active retrovirus for infecting hard-to-transfect cell lines, transfect the pSIREN-RetroQ-ZsGreen construct into a retroviral packaging cell line and collect the viral supernatant.

质粒图谱: