rndsystems FAB7098P说明书

rndsystems FAB7098P说明书

Human HLA Class I PE-conjugated Antibody

FAB7098P

人 HLA I 类 PE 偶联抗体

物种反应性
人类
特异性
检测人类主要组织相容性复合体 (MHC) I 类、HLA-A、B 和 C。识别 HLA-A、B 和 C 基因座产物之间共有的非多态性表位,并对 HLA 分子和 β2 进行免疫沉淀-微球蛋白。
资源
单克隆小鼠 IgG 2A克隆 # W6/32
纯化
从杂交瘤培养上清液中纯化的蛋白 A 或 G
免疫原
人扁桃体淋巴细胞的膜
公式
以含有 BSA 和叠氮化纳的盐水溶液形式提供。
标签
藻红蛋白(激发= 488 nm,发射= 565-605 nm)

数据示例

通过流式细胞术检测人血淋巴细胞中的 HLA I 类。 人外周血淋巴细胞用小鼠抗人 HLA I 类 PE 偶联单克隆抗体(货号 #FAB7098P,填充直方图)或同种型对照抗体(货号 # IC003P,开放直方图)染色。查看我们的膜相关蛋白染色方案。

准备和储存

船运
该产品随附极性包装。收到后,立即将其存放在以下推荐的温度下。
稳定性和存储
避光。不要冻结。

  • 自收货之日起 12 个月,2 至 8 °C(按原样提供)。

背景:HLA I 类

HLA-A、B 和 C 是主要组织相容性复合体 1 (MHC I) 家族中约 45 kDa 的跨膜糖蛋白。它们在细胞外区域包含三个 α 结构域。HLA 分子与 12 kDa β 2-微球蛋白结合在几乎所有有核细胞上表达。这种复合物结合源自致病性胞质或胞外蛋白(如病毒或微生物蛋白)的肽。它将这些肽呈递在细胞表面,以供 CD8+ 细胞毒性 T 细胞上的 T 细胞受体识别。然后活化的细胞毒性 T 细胞杀死呈递细胞。宿主和供体之间不匹配的 MHC I 等位基因导致移植排斥。

参考
  1. 巴恩斯特布尔,CJ等人。(1978) 单元格14 :9。

长名称
I类人白细胞抗原
Entrez 基因 ID
3105(人类)
备用名称
A-10 阿尔法链;FLJ26655; HLA I 类组织相容性抗原,A-1 α 链;HLA I 类组织相容性抗原,A-28 α 链;HLA I 类组织相容性抗原,A-9 α 链;HLA 一级;HLAA;HLA-A;HLA-ABC;主要组织相容性复合体,I 类,A;MHC I类抗原A*1;MHC I 类抗原 A*11;MHC I 类抗原 A*80

SciPac公司代理 fabp


SciPac公司代理 fabp

简要描述:SciPac(英国)是人类蛋白的主要制造商。SciPac因研发生产人的抗原而著名,此外,SciPac还提供大量人类血清和血浆,包括正常、处理和去除了某种成分的血清。

详细介绍

产品咨询

SciPac(英国)是人类蛋白的主要制造商。SciPac因研发生产人的抗原而著名,此外,SciPac还提供大量人类血清和血浆,包括正常、处理和去除了某种成分的血清。SciPac生产系列细胞培养蛋白,是世界上人转铁蛋白(Transferrins)的主要生产商。由于深受广大顾客欢迎,SciPac也针对供应的抗原提供相应的单抗和多抗。SciPac拥有自己的生物库,可供应疾病状态血浆、疾病状态血浆检测试剂盒和单个病人样品。SciPac全部通过了ISO 13485 和 ISO 9001认证。SciPac产品遍布*,60%销往美国。

 

2011年1月,SciPac公司研发出产品——脂肪酸结合蛋(FABP)上市,并可大量供应FABP。FABP主要在心脏和肝脏内发现。这些类似物通常区分于FABP3 (心脏)和 FABP1 (肝脏)。FABP是人的天然和重组的zui终产物,可用于各种诊断。

 

FABP分子量为14 kDa,根据分离的身体组织,它以不同类型存在。关于心脏来源的产品(FABP-H 或者FABP-3),一些研究表明,它也许是心肌梗死(Myocardial Infarction)比肌红蛋白(Myoglobin)更早期的标志物。肝脏类型(FABP-L 或者 FABP-1)是肾脏损伤尿液中的一个指标。

 

现在,SciPac有心脏天然和重组FABP可供您实验。
具体产品描述如下:
产品名称:
FABP Heart recombinant
心脏重组脂肪酸结合蛋白
FABP Liver recombinant
肝脏重组脂肪酸结合蛋白
FABP, Heart, FABP-3
心脏来源的脂肪酸结合蛋白,
脂肪酸结合蛋白-3
分类号:
P720-1
P721-1
P196-1
技术参数:
纯度>96%
纯度>96%
纯度>96%
来源:
酵母重组蛋白
酵母重组蛋白
人类心脏组织
Min Pk:
100 µg
100 µg
1 mg
外观:
冻干粉
冻干粉
冻干粉
贮存条件:
<-15°C
短期2-8°C ,长期<-15°C
2-8°C
Specification Abbreviation Min. Order  
ACTH Adrenocorticotropic Hormone > 98% pure 10 mg
  Albumin > 99% pure 2 mg
AFP Alpha Fetoprotein > 99% pure 1 mg
A1AGP Alpha-1-Acid Glycoprotein > 96% pure 1 mg
ACT Alpha-1-Antichymotrypsin > 90% pure 1 mg
A1AT Alpha-1-Antitrypsin > 96% pure 2 mg
A1M Alpha-1-Microglobulin > 96% pure 1 mg
A2M, α2M Alpha-2-Macroglobulin > 96% pure 2 mg
APO B Apolipoprotein B > 95% pure 1 mg
APO E Apolipoprotein E > 95% pure 100 µg
B2GP1, β2GP1 Beta-2-glycoprotein 1 > 96% pure 1 mg
B2M, β2M Beta-2-Microglobulin > 98% pure 2 mg
BNP, GC-B, Pro-BNP, NT-BNP Brain natriuretic peptide > 80% pure 250 µg
BCHE, BuChE Butyrylcholinesterase   100 U
CRP C Reactive Protein > 99% pure 2 mg
CA19-9 CA19-9 low cross contamination 10 KU
CEA Carcinoembryonic Antigen > 90% pure 100 µg
CD4 CD4 Antigen > 95% pure 100 µg
  Ceruloplasmin > 95% pure 1 mg
CHIK Chickungunya Antigen > 95% pure 1 mg
C1q Complement C1q > 96% pure 1 mg
CK, CK-MM, CK-MB, CK-BB Creatine Kinase > 10% pure 100 U
CYFRA 21-1 Cyfra 21-1 low cross contamination 500 µg
  Cystatin C > 96% pure 1 mg
D-D, DD, D-Di D-Dimer > 90% pure 1 mg
  Dengue Antigen > 95% pure 1 mg
ECP Eosinophil Cationic Protein > 98% pure 500 µg
FABP, FABP 3, FABP 1 Fatty Acid Binding Protein > 96% pure 1 mg
  Ferritin > 96% pure 1 mg
  Fibronectin > 99% pure 1 mg
FBP Folate Binding Protein > 95% pure 100 µg
GH Growth Hormone > 98% pure 1 mg
Hp Haptoglobin > 95% pure 1 mg
HbA1c Hemoglobin A1c > 96% pure 1 mg
HPX Hemopexin > 95% pure 1 mg
HBV, HBsAg Hepatitis B Antigen > 92% pure 1 mg
HDL High Density Lipoprotein >99% HDL compared to LDL 1 g
hCG Human Chorionic Gonadotropin > 65% pure 1 mega IU
Abbreviation Product Name Specification Min. Order
CRP C Rreactive Protein Depleted Serum < 200 ng/ml 500 ml
  Homocystein Depleted Serum < 2 µmol/L 500 ml
  Hormones Depleted Serum FSH = <0.2 IU/L | hCG = < 1.0 IU/L | LH= < 0.2 IU/L 500 ml
  Immunoglobulins Depleted Serum < 5 IU/ml 500 ml
  Insulin Depleted Serum < 1 MIU/L 500 ml
  Steroid Depleted Serum Progesterone = < 0.5 nmol/L | Estradiol = < 0.07 nmol/L | Testosterone = < 0.4nmol/L 500 ml
  T3 and T4 Depleted Serum Total T4 = < 20 nmol/L | Total T3 = < 1.0 nmol/L | Free T4 = < 1.0 pmol/L | Free T3 = < 5.0 pmol/L 500 ml
TSH Thyroid Stimulating Hormone Depleted Serum < 0.05 MIU/L 500 ml
  Troponin I Depleted Serum < 0.03 µg/L 500 ml
Vit. D Vitamin D Depleted Serum < 10 nmol/L 500 ml
       
Abbreviation Product Name Specification Min. Order
  Allergy Serum/Plasma Plasma from patients with a recognised allegy 10 ml
AFP Alpha Fetoprotein Positive Serum/Plasma Measured AFP levels 10 ml
ACP Anti Citrullinated Peptide Antibodies Positive Serum/Plasma Positive for ACP Antibodies 10 ml
  Anti-Steptolysin Positive Serum/Plasma Positive for Anti-Steptolysin 10 ml
ANA Antinuclear Antibodies Positive Serum/Plasma Positive for ANA 10 ml
APLS Antiphospholipid Syndrome Positive Serum/Plasma Positive diagnosis for Antiphospholipid Syndrome 10 ml
  Beta-2-Glycoprotein 1 Positive Serum/Plasma Positive for B2GP1 10 ml
  Billirubin Positive Serum/Plasma Positive for Billirubin 10 ml
  Borellia Birgdoferi (Lyme) Positive Serum/Plasma Positive for Lyme IgG 10 ml
  Brain Naturic Peptide Clinical Patient Samples    
  C Reactive Protein Clinical Patient Samples    
  C Reactive Protein Positive Serum/Plasma Measured CRP levels 100 ml
  C-Peptide Clinical Patient Samples    
  CA125 Clinical Patient Samples    
CA125 CA125 Positive Serum/Plasma Positive for CA125 10 ml
CA15-3 CA15-3 Positive Serum/Plasma Positive for CA15-3 10 ml
  CA19-9 Positive Serum/Plasma Positive for CA19-9 10 ml
  Carcino Embryonic Antigen Clinical Patient Samples    
CEA Carcinoembryonic Antigen Positive Serum/Plasma Measured CEA levels 100 ml
  Cardiolipin Antibodies Positive Serum/Plasma Positive for Cardiolipin IgA Antibodies 10 ml
  Celiac Disease Clinical Patient Samples    
  Celiac Disease Positive Serum/Plasma Positive diagnosis for Celiac Disease 10 ml
  CK-MB Clinical Patient Samples    
C1q Complement C1q Positive Serum/Plasma Positive for C1q 10 ml
  Contraceptive Pill Positive Serum/Plasma From patients taking the contraceptive pill 10 ml
CREST CREST Positive Serum/Plasma Positive diagnosis for CREST disease 10 ml
  Crohn’s Disease Clinical Patient Samples    
  Cyclic Citrullinated Peptide Antibodies Positive Serum/Plasma Positive for CCP Antibodies 10 ml
  Cytomeglovirus Positive Serum/Plasma Positive for CMV IgG 10 ml
  D-Dimer Clinical Patient Samples    
  Diabetes Clinical Patient Samples    
  Diabetes Positive Serum/Plasma Positive for Diabetes Type 1 10 ml
  dsDNA Positive Serum/Plasma Positive for dsDNA 10 ml
EBV Epstein Barr Virus Positive Serum/Plasma Positive for EBV IgM 10 ml
  Erythropointin Clinical Patient Samples    
  Estradiol Clinical Patient Samples    
FSH Follicle Stimulating Hormone Clinical Patient Samples    
  Follicle Stimulating Hormone Positive Serum/Plasma Measured FSH levels 100 ml
  Ganglioside antibodies Clinical Patient Samples    
  Glomerular Basement Membrane Antibodies Elevated Serum/Plasma Positive for GBM Antibodies 10 ml
  Graves Disease Clinical Patient Samples    
  Graves Disease Positive Serum/Plasma Positive diagnosis of Graves disease 10 ml
  Growth Hormone Clinical Patient Samples    
  H. Pylori Positive Serum/Plasma Positive for H. Pylori IgG 10 ml
HAMA HAMA Positive Serum/Plasma Positive for HAMA 10 ml
  Hashimotos Disease Clinical Patient Samples    
  Hashimotos Disease Positive Serum/Plasma Positive diagnosis of Hashimotos Disease 10 ml
Aflatoxin B mAb Aflatoxin B Monoclonal Antibody Protein G Purified 1 mg
AFP mAb Alpha Fetoprotein Monoclonal Antibody Protein G Purified 1 mg
ahCG mAb alpha human Chorionic Gonadotropin Monoclonal Antibody Protein G Purified 1 mg
bhCG beta human Chorionic Gonadotropin Monoclonal Antibody Protein G Purified 1 mg
B2M mAb, hB2M mAb Beta-2-Microglobulin Monoclonal Antibody Affinity purified 1 mg
CRP mAb C Reactive Protein Monoclonal Antibody Protein A Purified 1 mg
CA125 mAb CA125 Monoclonal Antibody Affinity Purified 1 mg
CA15-3 mAb CA15-3 Monoclonal Antibody Protein G Purified 1 mg
CA19-9 mAb CA19-9 Monoclonal Antibody Protein A Purified 1 mg
CT mAb, HCT mAb Calcitonin Monoclonal Antibody Affinity Purified 1 mg
Calprotectin mAb Calprotectin Monoclonal Antibody Affinity Purified  
CEA mAb Carcinoembryonic Antigen Monoclonal Antibody Protein A Purified 1 mg
CHIKV mAb Chikungunya Monoclonal Antibody Protein G Purified 1 mg
Cortisol mAb Cortisol Monoclonal Antibody Affinity Purified 1 mg
CK-MB mAb Creatine Kinase (CK-MB) Monoclonal Antibody Affinity Purified 1 mg
Cystatin C mAb Cystatin C Monoclonal Antibody Protein G Purified 1 mg
CK19 mAb Cytokeratin 19 Monoclonal Antibody Protein A Purified 1 mg
D-D mAb D-Dimer Monoclonal Antibody Prrotein A Purified 1 mg
DHEA mAb, DHEA sulphate mAb Dehydroepiandrosterone, sulphate Monoclonal Antibody Affinity Purified 1 mg
Dengue mAb Dengue NS1 Monoclonal Antibody Affinity Purified 1 mg
Estriol mAb Estriol Monoclonal Antibody Affinity Purified 1 mg
Ev71 mAb Ev71 Monoclonal Antibody Affinity Purified 1 mg
FSH mAb Follicle Stimulating Hormone Monoclonal Antibody Protein A Purified 1 mg
GH mAb, hGH mab Growth Hormone Monoclonal Antibody Affinity Purified 1 mg
H. Pylori mAb H. Pylori Monoclonal Antibody Protein G Purified 1 mg
HbA1c mAb HbA1c Monoclonal Antibody Protein G Purified 1 mg
Hb mAb Hemoglobin Monoclonal Antibody Protein G Purified 1 mg
Abbreviation Product Name Specification Min. Order
HbA1c HbA1c Reagent for Boronate Affinity and Immunoassay < 3.5% HbA1c (DCCT Aligned) 10 ml
HbA1c HbA1c Reagent for HPLC < 20 nmol/mol (IFCC Aligned) 10 ml